Document 0578
 DOCN  M9480578
 TI    CT of primary colonic lymphoma.
 DT    9410
 AU    Wyatt SH; Fishman EK; Hruban RH; Siegelman SS; Russell H. Morgan
       Department of Radiology and Radiological; Science, Johns Hopkins Medical
       Institutions, Baltimore, Maryland.
 SO    Clin Imaging. 1994 Apr-Jun;18(2):131-41. Unique Identifier : AIDSLINE
       MED/94306283
 AB    The article presents the computed tomography (CT) findings in 15
       patients with histopathologically proven primary lymphoma of the
       colorectum. CT is invaluable for the characterization of primary colonic
       lymphomas and for definition of tumor invasion and spread. The lymphomas
       in our series were categorized according to their CT appearance as
       either discrete bulky masses (n = 6), focal mural infiltration (n = 5),
       or diffuse colonic invasion (n = 5). Primary colonic lymphomas that were
       manifested as mass lesions had a greater depth of mural invasion (x =
       4.3 cm) than did infiltrative lesions (x = 2.7 cm, P < .05), and tended
       to present at an earlier stage. In the setting of solitary mass lesions
       in the colon that are not associated with adenopathy, CT findings can
       help to distinguish primary lymphoma from adenocarcinoma. Cecal tumors
       that grow into the terminal ileum, tumors which are fairly well
       demarcated from the surrounding pericolonic fat and show no evidence of
       invasion or obstruction of neighboring viscera, and tumors which
       perforate in the absence of desmoplastic reaction should suggest
       lymphoma. A clinical history of human immunodeficiency virus infection
       should also prompt consideration of colonic lymphoma.
 DE    Adenocarcinoma/PATHOLOGY/RADIOGRAPHY  Adult  Aged  Colonic
       Neoplasms/PATHOLOGY/*RADIOGRAPHY  Diagnosis, Differential  Female  Human
       Lymphoma/PATHOLOGY/*RADIOGRAPHY  Lymphoma,
       AIDS-Related/PATHOLOGY/RADIOGRAPHY  Male  Middle Age  Neoplasm
       Invasiveness  Rectal Neoplasms/PATHOLOGY/*RADIOGRAPHY  *Tomography,
       X-Ray Computed  JOURNAL ARTICLE

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